Immunotherapy for Pediatric Malignancies (3319434845)

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This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical aspects of delivering such therapies to children, likely toxicities and potential biomarkers are considered. Finally, consideration is given to how, in the longer term, such therapies may be combined with conventional therapies such as chemotherapy and radiotherapy.

Edited by two distinguished pediatric oncologists with a collection of chapters from the most authoritative experts in cancer immunotherapy, this is an indispensable volume for pediatric oncologists and physicians working in childhood cancer care.

Product details

• Format Hardback | 297 pages
• Dimensions 155 x 235 x 21.59mm | 5,843g
• Publication date 05 Dec 2017
• Publisher Springer International Publishing AG
• Publication City/Country Cham, Switzerland
• Language English
• Edition Statement 1st ed. 2018
• Illustrations note 27 Illustrations, color; 2 Illustrations, black and white; IX, 297 p. 29 illus., 27 illus. in color.
• ISBN10 3319434845
• ISBN13 9783319434841

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